PCL was chosen because of its good mechanical properties and its compatibility with many types of polymers, and because it is one of the more hydrophobic of the commercially available biodegradable polymer (Koleske, 1978)
Wednesday, October 24, 2012
Polycaprolactone
Polycaprolactone (PCL) has been thoroughly studied as a substarte for biodegradation (Potts, 1984) and as a matrix in controlled-release systems for drugs (Pitt et al.,1980). Its degradation in vivo is much slower than that of poly (α-hydroxy acid). Thus, it is most suitable for controlled-release devices with long in vivo lifetimes. PCL is generally prepared from the ring-opening polymerization of ε-caprolactone.
PCL was chosen because of its good mechanical properties and its compatibility with many types of polymers, and because it is one of the more hydrophobic of the commercially available biodegradable polymer (Koleske, 1978)
PCL was chosen because of its good mechanical properties and its compatibility with many types of polymers, and because it is one of the more hydrophobic of the commercially available biodegradable polymer (Koleske, 1978)
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment